Jay Leno takes over the Tonight Show with interview, sketches, and plenty of laughs.
After Johnny Carson 's retirement from the show, Jay Leno stepped in as his permanent replacement. The format of the show has remained largely unchanged, consisting primarily of an opening humorous monologue, followed by several celebrity interviews, comedy sketches and musical numbers.
1. Howie Mandel, Amanda Bynes, Emmylou Harris
Aired: Sep 17, 2007
2. Jamie Foxx, Tim Gunn, Paolo Nutini
Aired: Sep 18, 2007
3. Dane Cook, Ali Larter, LCD Soundsystem
Aired: Sep 19, 2007
4. Jessica Alba, D.L. Hughley, Cold War Kids
Aired: Sep 20, 2007
5. Pamela Anderson/Mary J. Blige
Aired: Sep 21, 2007
6. Dwayne "The Rock" Johnson, Dennis Kucinich, Diana Krall
Aired: Sep 24, 2007
7. Jennifer Love Hewitt, Jeff Corwin, Reba McEntire with Vince Gill
Aired: Sep 25, 2007
8. Steve Carell, Madison Pettis, Bright Eyes
Aired: Sep 26, 2007
9. Ben Stiller, Tony Snow, Raul Midon
Aired: Sep 27, 2007
10. Teri Hatcher, Kevin McKidd, Queen Latifah
Aired: Sep 28, 2007Blondes tell blonde jokes.
11. Patricia Heaton, Emeril Lagasse, Tori Amos
Aired: Oct 1, 2007
13. Tom Selleck, Carlos Mencia, Bobbie and Willie Nelson
Aired: Oct 3, 2007
14. John Larroquette, Chelsea Handler, Matchbox Twenty
Aired: Oct 4, 2007
15. Cate Blanchett, Tyler Perry, Annie Lennox
Aired: Oct 5, 2007
16. Ben Affleck, Jim Norton, The Shins
Aired: Oct 8, 2007
17. Jaime Pressly, Brady Barr, Blue Man Group
Aired: Oct 9, 2007
18. Dana Carvey, Malin Akerman, Plain White T's
Aired: Oct 10, 2007
19. Joaquin Phoenix, Gordon Ramsay, Vanessa Carlton
Aired: Oct 11, 2007
20. Christina Applegate, Bill O'Reilly, Alicia Keys
Aired: Oct 12, 2007
21. James Spader, Lara Logan, Steve Byrne
Aired: Oct 15, 2007
22. Reese Witherspoon, David Koechner, PJ Harvey
Aired: Oct 16, 2007
23. Sen. Barack Obama, Orny Adams, Keith Urban
Aired: Oct 17, 2007
24. Jerry Seinfeld, Amy Ryan, Evanescence
Aired: Oct 18, 2007
25. Halle Berry, Greg Grunberg, Dwight Yoakam
Aired: Oct 19, 2007
26. Russell Crowe, Jenna Bush, Carrie Underwood
Aired: Oct 29, 2007
27. Tom Cruise, Rep. Ron Paul, Sex Pistols
Aired: Oct 30, 2007
28. Eva Mendes, Marjorie Johnson, Barry Manilow
Aired: Oct 31, 2007
29. Denzel Washington, Dave Salmoni, LeAnn Rimes
Aired: Nov 1, 2007
30. Steve Carell, Manny Ramirez, Backstreet Boys
Aired: Nov 2, 2007
31. Gov. Mike Huckabee, Emeril Lagasse, Chingy
Aired: Jan 2, 2008
32. Howie Mandel, Jason Lewis, Joe Nichols
Aired: Jan 3, 2008
33. Animals With Jarod Miller, John Caparulo, Blake Lewis
Aired: Jan 4, 2008
34. Ron Paul, Christopher Titus, Shakira
Aired: Jan 7, 2008
35. Pamela Anderson, Mary J. Blige
Aired: Jan 8, 2008
36. Jules Sylvester and animals, Maria Bartiromo, Finger Eleven
Aired: Jan 9, 2008
37. Jimmy Kimmel, Elon Gold, OneRepublic
Aired: Jan 10, 2008
38. Arsenio Hall, Melanie Metz & Peggy Willenberg, Seether
Aired: Jan 11, 2008
39. Marilu Henner, Brady Barr, Jordan Sparks
Aired: Jan 14, 2008
40. Bill Maher, Carrie Ann Inaba & Bruno Tonioli, Taylor Swift
Aired: Jan 15, 2008
41. Chris Matthews, John Roy, Jill Scott
Aired: Jan 16, 2008
42. D.L. Hughley, Joe Ligotti, Sara Bareilles
Aired: Jan 17, 2008
43. Mitt Romney, Ryan Sheckler, Jonas Brothers
Aired: Jan 18, 2008
44. Simon Cowell & Ryan Seacrest, Tavis Smiley, Shaggy
Aired: Jan 21, 2008
45. David Gregory, Performing Birds, Puddle Of Mudd
Aired: Jan 22, 2008
46. Adam Carolla, Richard Roeper, Shooter Jennings
Aired: Jan 23, 2008
47. Animals With Julie Scardina, Chelsea Handler, Buckcherry
Aired: Jan 24, 2008
48. Hulk Hogan, Mad Scientist David Willey, Natasha Bedingfield
Aired: Jan 25, 2008
49. Chazz Palminteri, Alison Sweeney, Dierks Bentley
Aired: Jan 28, 2008
50. Lester Holt, Blue Ribbon Baker Marjorie Johnson, Raheem DeVaughn
Aired: Jan 29, 2008
51. Ryan Phillippe/Lisa Lampanelli/Jim Lauderdale
Aired: Jan 30, 2008Actor Ryan Phillippe (Stop-Loss (2008)); actress Lisa Lampanelli (Drillbit Ta...
52. Sen. John McCain, Rudy Giuliani, Shelby Lynne
Aired: Jan 31, 2008
53. Tom Brokaw, Terrell Owens, Graham Colton
Aired: Feb 1, 2008
54. Dan Rather, Mike Rowe, Josh Kelley
Aired: Feb 4, 2008
55. Insects with Brent Karner, Stephen Baldwin, J. Holiday
Aired: Feb 5, 2008
56. Frank Caliendo, Chimp Rescuer Eugene Cussons, Flo Rida
Aired: Feb 6, 2008
57. Arsenio Hall, Paula Deen, James Blunt
Aired: Feb 7, 2008
58. Brian Williams, Ahmed Ahmed, Enrique Iglesias
Aired: Feb 8, 2008
59. Larry the Cable Guy, Bobby Knight, Andrea Bocelli
Aired: Feb 11, 2008
60. Larry the Cable Guy, Bruno Tonioli, Glen Hansard & Markéta Irglová
Aired: Feb 12, 2008
61. Joan Embery and Animals, Larry the Cable Guy, Mika
Aired: Feb 13, 2008
62. Russell Crowe, Larry the Cable Guy, Willie Nelson
Aired: Feb 14, 2008
63. Kristen Chenoweth, Russell Peters, Lifehouse
Aired: Feb 15, 2008
64. Reese Witherspoon, Alex Cambert, Gary Allan
Aired: Feb 18, 2008
65. Will Ferrell, Hayden Christensen, The Hives
Aired: Feb 19, 2008
66. Garth Brooks, Christina Ricci
Aired: Feb 20, 2008
67. Heidi Klum, James McAvoy, John Fogerty
Aired: Feb 21, 2008
68. Colin Farrell, Bill O'Reilly, Herbie Hancock
Aired: Feb 22, 2008
69. Eric Bana, Catherine O'Hara, Tift Merritt
Aired: Feb 25, 2008
70. Dennis Quaid, David Koechner, Lupe Fiasco
Aired: Feb 26, 2008
71. Billy Ray Cyrus, Miley Cyrus, Brooke Shields
Aired: Feb 27, 2008
72. Wanda Sykes, Bryan Cranston, Cat Power
Aired: Feb 28, 2008
73. Dave Salmoni and Animals, Patricia Arquette, The Punch Brothers
Aired: Feb 29, 2008
74. Dominic Monaghan, Ethan Bortnick, Sheryl Crow
Aired: Mar 10, 2008
75. America Ferrera, Bob Saget, The Blind Boys of Alabama
Aired: Mar 11, 2008
76. Bill Cosby, Novak Djokovic, Landon Pigg
Aired: Mar 12, 2008
77. Howie Mandel, Minnie Driver
Aired: Mar 13, 2008
Aired: Oct 11, 2007
79. Kate Beckinsale, Carlos Mencia, The Bravery
Aired: Mar 17, 2008
80. Terry Bradshaw, James Carville & Mary Matalin, Michael McDonald
Aired: Mar 18, 2008
81. Ryan Phillippe, Lisa Lampanelli, Jim Lauderdale
Aired: Mar 19, 2008
82. John Edwards, Leslie Mann, Nada Surf
Aired: Mar 20, 2008
83. Adam Carolla, Geraldo Rivera, The Black Crowes
Aired: Mar 21, 2008
84. Peter O'Toole, Katt Williams, Leona Lewis
Aired: Mar 24, 2008
85. Abigail Breslin, Seth Meyers, Steve Earle
Aired: Mar 25, 2008
86. John Krasinski, Joe Torre, José González
Aired: Mar 26, 2008
87. Conan O'Brien, Anderson Cooper, Allison Moorer
Aired: Mar 27, 2008
88. John Larroquette, Kid Inventors, k.d. lang
Aired: Mar 28, 2008
89. Jodie Foster, Cedric the Entertainer, Lili Haydn
Aired: Mar 31, 2008
90. Mike Huckabee; Emeril Lagasse; Chingy
Aired: Jan 2, 2008Republican Presidential Candidate Mike Huckabee; Chef Emeril Lagasse; Chingy ...
91. Steve Carell, Kathie Lee Gifford, Ani DiFranco
Aired: Apr 2, 2008
92. Sen. Hillary Clinton, Patton Oswalt, Ferras
Aired: Apr 3, 2008
93. David Spade, Nora Hardwick, Ben Lee
Aired: Apr 4, 2008
94. Pamela Anderson; Mary J. Blige
Aired: Jan 8, 2008Pamela Anderson; Mary J. Blige performs from the CD "Growing Pains."
95. Jules Sylvester; Maria Bartiromo; Finger Eleven
Aired: Jan 9, 2008Jules Sylvester and reptiles; Maria Bartiromo; Finger Eleven performs from th...
96. Jimmy Kimme; Elon Gold; OneRepublic
Aired: Jan 10, 2008From "jimmy kimme live!," Jimmy Kimme; Stand-up comedian, Elon Gold; the musi...
97. Keanu Reeves, Chelsea Handler, The Redwalls
Aired: Apr 10, 2008
98. William Shatner, Tricia Helfer, Ryan Bingham
Aired: Apr 11, 2008
99. Mark Harmon, Corbin Maxey, Ray J
Aired: Apr 14, 2008
100. Brad Garret; Ingrid Michaelson; John Melendez
Aired: Apr 15, 2008Brad Garrett from "Til Death" and John Melendez from "One, Two, Many". The mu...
101. Charles Barkley, The Young@Heart Chorus
Aired: Apr 16, 2008
102. Ewan McGregor, John Cho & Kal Penn, Seether
Aired: Apr 17, 2008
103. Tracey Ullman, Jason Taylor, Flogging Molly
Aired: Apr 18, 2008
104. Dave Salmoni, Norm MacDonald, Ashlee Simpson
Aired: Apr 21, 2008
105. Julia Louis-Dreyfus, Jason Segel, Goldfrapp
Aired: Apr 22, 2008
106. Patrick Dempsey, Ed Begley Jr., Tegan and Sara
Aired: Apr 23, 2008
107. Gov. Arnold Schwarzenegger, Marilu Henner, Old 97's
Aired: Apr 24, 2008
108. Hugh Laurie, Doug Fine, Prince
Aired: Apr 25, 2008
109. Helen Hunt, Gov. Bobby Jindal, Duffy
Aired: Apr 28, 2008
110. Dr. Phil McGraw, the Lopez family, Natasha Bedingfield
Aired: Apr 29, 2008
111. Cindy McCain, Ed Helms, Augustana
Aired: Apr 30, 2008
112. Robin Williams, Terrence Howard, Serj Tankian
Aired: May 1, 2008
113. Sally Field, Jesse Ventura, Sleepercar
Aired: May 2, 2008
114. Robert Downey Jr., Carlos Mencia, Rascal Flatts
Aired: May 5, 2008
115. Julie Scardina and animals, Christina Ricci, KT Tunstall
Aired: May 6, 2008
116. Former President Jimmy Carter, Jon Favreau, P.O.D.
Aired: May 7, 2008
117. Jenna Fischer, Robert Schimmel, Trace Adkins
Aired: May 8, 2008
118. Harrison Ford, William Moseley, Carly Simon
Aired: May 9, 2008
Aired: May 12, 2008
120. Evangeline Lilly, Ben Barnes, Switchfoot
Aired: May 13, 2008
121. Rainn Wilson, Howard Dean, Kate Nash
Aired: May 14, 2008
122. Dana Delany, Adam Carolla, Dwight Yoakam
Aired: May 15, 2008
123. Matthew Fox, Kathleen Edwards
Aired: May 16, 2008
124. Simon Cowell, Rob Schneider, Josh Groban
Aired: May 19, 2008
125. Sylvester Stallone, Irma & Ray Ziff, Jason Mraz
Aired: May 20, 2008
126. Adam Sandler, Hilary Duff, Al Green
Aired: May 21, 2008
127. Laura & Jenna Bush, David Cook, Tristan Prettyman
Aired: May 22, 2008
128. Terry Bradshaw, Turkey Baster Virtuoso Ray Sanders, Colbie Caillat
Aired: May 23, 2008
129. William Shatner, Chelsea Handler, Newton Faulkner
Aired: Jun 2, 2008
130. Liv Tyler, Judd Apatow, Usher
Aired: Jun 3, 2008
131. Jeff Foxworthy, Arianna Huffington, N.E.R.D.
Aired: Jun 4, 2008
132. Dave salmoni; Patricia Arquette; Punch Brothers
Aired: Feb 29, 2008Amazing animals with Dave salmoni! From "medium" Patricia Arquette! The music...
133. Will Smith, Pete Sampras, Ed Harcourt
Aired: Jun 6, 2008
134. Russel Brand, Bill Engvall, Aimee Mann
Aired: Jun 9, 2008
135. Justin Timberlake, Karen Allen, Sheryl Crow
Aired: Jun 10, 2008
136. Dana Carvey, Spencer Breslin, Priscilla Ahn
Aired: Jun 11, 2008
137. Mike Myers, Abigail Breslin, David Cook
Aired: Jun 12, 2008Doc Brown shows you the most efficient way to incorporate seasonality into yo...
138. Larry the Cable Guy, Bob Costas, Ashanti
Aired: Jun 13, 2008
139. Anne Hathaway; Gabriel Iglesias; Amos Lee
Aired: Jun 16, 2008Anne Hathaway "Get Smart" - Comedian Gabriel Iglesias; Amos Lee: Performance ...
140. Ryan Phillippe; Lisa Lampanelli; Jim Lauderdale
Aired: Mar 19, 2008Ryan Phillippe from "Stop-Loss", Lisa Lampanelli from "Drillbit Taylor" and m...
141. Dwayne "The Rock" Johnson, Tom Papa, Against Me!
Aired: Jun 18, 2008
142. Wanda Sykes, James McAvoy, Duffy
Aired: Jun 19, 2008
Aired: Jun 20, 2008
144. Selma Blair, Kevin Nealon, Steve Tyrell
Aired: Jul 7, 2008
145. Aaron Eckhart, Dara Torres, Los Lonely Boys
Aired: Jul 8, 2008
146. Animal Expert Jarod Miller, David Koechner, Sara Bareilles
Aired: Jul 9, 2008
147. Conan O'Brien; Anderson Cooper; Allison Moorer
Aired: Mar 27, 2008Conan O'Brien; Anderson Cooper; Allison Moorer: Performance from the CD "Mock...
148. John Larroquette; Kid Inventors; K.D. Lang
Aired: Mar 28, 2008John Larroquette "Boston Legal"; Kid Inventors; K.D. Lang: Performance from t...
149. Jodie Foster; Cedric the Entertainer; Lili Hayden
Aired: Mar 31, 2008Jodie Foster, Cedric the Entertainer, the music of Lili Hayden and "headlines."
150. David Beckham; Sherri Shepherd; B-52s
Aired: Apr 1, 2008Soccer great, David Beckham, from "the view," Sherri Shepherd, the music of t...
151. Steve Carell; Kathie Lee Gifford; Ani LiFranco
Aired: Apr 2, 2008Steve Carell; from the "Today" Show, Kathie Lee Gifford. The music of Ani LiF...
152. Hillary Clinton; Patto Oswalt; Ferras
Aired: Apr 3, 2008Senator Hillary Clinton, comedian Patto Oswalt; the Music of Ferras, and "jay...
153. David Spade; Nora Hardwick; Ben Lee
Aired: Apr 4, 2008David Spade "Rules of Engagement"; 102-year-old Nora Hardwick, Britain's olde...
154. Thomas Haden Church; Sig & Edgar Hansen; Jimmy Eat World
Aired: Apr 7, 2008Thomas Haden Church from "Smart People", Sig & Edgar Hansen from "The Deadlie...
155. Dennis Quaid; Russell Brand; Brett Dennen
Aired: Apr 8, 2008Dennis Quaid from "Smart People", Russell Brand from "Forgetting Sarah Marsha...
156. Ellen Page; Donny & Marie Osmond; Angie Stone
Aired: Apr 9, 2008Ellen Page from "Smart People", Donny & Marie Osmond from the "Miss USA Pagea...
157. Keanu Reeves; Chelsea Handler; The Redwalls
Aired: Apr 10, 2008Keanu Reeves from the movie "Street Kings", Chelsea Handler, the music of The...
158. William Shatner; Tricia Helfer; Ryan Bingham
Aired: Apr 11, 2008William Shatner from "Boston Legal", Tricia Helfer from "Battlestar Galactica...
159. Mark Harmon; Corbin Maxey; Ray J
Aired: Apr 14, 2008Mark Harmon from "NCIS" and 18-year-old reptile expert Corbin Maxey. The musi...
160. Brad Garrett; John Melendez; Ingrid Michaelson
Aired: Apr 15, 2008Brad Garrett from "Til Death" and John Melendez from "One, Two, Many". The mu...
161. Charles Barkley; Young @ Heart Chorus
Aired: Apr 16, 2008Charles Barkley and 3 Senior Rock Stars from "Young @ Heart Chorus". The musi...
162. Rosie Perez, Robin Thicke
Aired: Jul 31, 2008
163. Bill Cosby, Emma Stone, John Mellencamp with T Bone Burnett
Aired: Aug 1, 2008
164. Ben Stiller, Jonas Brothers
Aired: Aug 4, 2008
165. Robert Downey Jr., Anna Faris, Toby Keith
Aired: Aug 5, 2008
166. Jack Black, Pillsbury Bake-Off-Champ Carolyn Gurtz, Conor Oberst
Aired: Aug 6, 2008
167. Nick Nolte, Carrot Top, Solomon Burke
Aired: Aug 7, 2008
168. Hugh Laurie; Doug Fine; Prince
Aired: Apr 25, 2008Hugh Laurie "House"; Doug Fine "Environmental Author"; Prince: Performance fr...
169. Sen. John McCain, Dara Torres, Juliana Hatfield
Aired: Aug 25, 2008
170. Norm MacDonald, Nastia Liukin, B.B. King
Aired: Aug 26, 2008
171. Bill Maher, Henry Cejudo, Low vs Diamond
Aired: Aug 27, 2008
172. Gordon Ramsay, Natalie Coughlin, Missy Higgins
Aired: Aug 28, 2008
173. Arsenio Hall, Shawn Johnson, Chuck Berry
Aired: Aug 29, 2008
174. Russell Brand, Eva Longoria Parker, Ingrid Michaelson
Aired: Sep 2, 2008
175. Billy Bob Thornton, Ethan Bortnick, Brian Wilson
Aired: Sep 3, 2008
176. Howie Mandel, Sanya Richards, The Game
Aired: Sep 4, 2008
177. Jenna Fischer; Robert Schimmel; Trace Adkins
Aired: May 8, 2008Jenna Fischer "The Office"; Comedian Robert Schimmel; Trace Adkins: Performin...
178. Harrison Ford; William Moseley; Carly Simon
Aired: May 9, 2008Harrison Ford "Indiana Jones"; William Moseley "The Chronicles of Narnia Prin...
179. Jules Sylvester, Annette Bening, Leona Lewis
Aired: Sep 9, 2008
180. Matthew McConaughey, T. Boone Pickens, Al Green
Aired: Sep 10, 2008
181. Jamie Lee Curtis, Jerome Bettis, Alejandro Escovedo
Aired: Sep 11, 2008
182. Hugh Laurie, Dame Edna, Raphael Saadiq
Aired: Sep 12, 2008
183. Matthew Fox; Kathleen Edwards
Aired: May 16, 2008Matthew Fox "Speed Racer"; Kathleen Edwards: Performance from the CD "Asking ...
184. Simon Cowell; Rob Schneider; Josh Groban
Aired: May 19, 2008Simon Cowell "American Idol"; Rob Schneider "You Don't Mess with the Zohan"; ...
185. Sylvester Stallone; Irma & Ray Ziff; Jason Mraz
Aired: May 20, 2008Sylvester Stallone "Rambo"; Couple married 75 yrs. Irma & Ray Ziff; Jason Mra...
186. Adam Sandler; Hillary Duff; Al Green
Aired: May 21, 2008Adam Sandler "You Don't Mess with the Zohan"; Hillary Duff "War, Inc."; Al Gr...
187. Laura & Jenna Bush; David Cook; Tristan Prettyman
Aired: May 22, 2008Laura & Jenna Bush; American Idol winner David Cook; Tristan Prettyman: Perfo...
188. Terry Bradshaw; Ray Sanders; Colbie Caillat
Aired: May 23, 2008Terry Bradshaw; Turkey baster virtuoso Ray Sanders; Colbie Caillat: Performan...
194. Ellen Degeneres; Jerry O'Connell; Jazmine Sullivan
Aired: Sep 30, 2008Main Cast
Appearances
