1. Robin Thicke
Aired: Jan 4, 2010 We're starting off the new year with Robin Thicke and his Sex Therapy...like ...
2. Mary J. Blige
Aired: Jan 5, 2010 We're getting deep with Mary J. Blige and her new album, Stronger With Each T...
3. Holly Madison
Aired: Jan 6, 2010 We're getting deep with Mary J. Blige and her new album, Stronger With Each T...
4. Joel David Moore
Aired: Jan 7, 2010 Holly Madison is dropping on by her old E! family today...we've missed her, t...
5. Giuliana & Bill Rancic
Aired: Jan 11, 2010 Word on the street is Giuliana and Bill Rancic are trying to have a baby. Wha...
6. Aisha Tyler
Aired: Jan 12, 2010 We welcome back the very funny Aisha Tyler, from the new show Archer. Comedia...
7. Amy Brenneman
Aired: Jan 13, 2010 Amy Brenneman of Private Practice stops by, perhaps with some doctorly advice...
8. Snooki, Pauly D and The Situation
Aired: Jan 14, 2010 Fist pumps all around for Jersey Shore's Snooki, Pauly D and The Situation. C...
9. David Arquette
Aired: Jan 18, 2010 David Arquette is back and telling us all about his new play The Female of th...
10. Adrianne Palicki
Aired: Jan 19, 2010 Clear eyes, full hearts, can't lose with Legion's Adrianne Palicki (aka FNL's...
11. Kaley Cuoco
Aired: Jan 20, 2010 Who wouldn't be stoked that Kaley Cuoco from the megapopular Big Bang Theory ...
12. James Van Der Beek
Aired: Jan 21, 2010 James Van Der Beek is in the new movie Formosa Betrayed and popping up all ov...
13. Katharine McPhee
Aired: Jan 25, 2010
14. Jill Scott
Aired: Jan 26, 2010
15. Dax Shepard
Aired: Jan 27, 2010
16. Staff Book Club
Aired: Jan 28, 2010
17. Camila Alves
Aired: Feb 1, 2010
18. Andy Whitfield
Aired: Feb 2, 2010
19. Shorty Rossi
Aired: Feb 3, 2010
20. Julie Benz
Aired: Feb 4, 2010
21. Ozzy Osbourne
Aired: Feb 8, 2010
22. Amanda Seyfried
Aired: Feb 9, 2010
23. Dave Salmoni
Aired: Feb 10, 2010 We're beyond pleased to welcome back our animal guy Dave Salmoni and his new ...
24. Channing Tatum
Aired: Feb 12, 2010
25. Kate Flannery
Aired: Feb 15, 2010 We get down to business with The Office's Kate Flannery. Comedian Loni Love, ...
26. Jackie Collins
Aired: Feb 16, 2010 Things get really scandalous when author Jackie Collins stops by with her new...
27. Lisa Edelstein
Aired: Feb 17, 2010 Lisa Edelstein from House is back again...Wait, so who's running Princeton Pl...
28. Eli Roth
Aired: Feb 18, 2010
29. Keshia Knight Pulliam
Aired: Feb 22, 2010 House of Payne's Keshia Knight Pulliam is one hard working lady; Dr. Huxtable...
30. Danica Patrick
Aired: Feb 23, 2010 We're pretty thrilled that Danica Patrick makes a pit stop over at Chelsea La...
31. Radha Mitchell
Aired: Feb 24, 2010 Things might get wild with Radha Mitchell star of the new thrilling horror mo...
32. Parker Posey
Aired: Feb 25, 2010 The Chelsea Lately cast do a Kardashian skit. Comedian Brad Wollack, comedian...
33. Sean William Scott
Aired: Mar 1, 2010 From the new movie Cop Out we've got Seann William Scott in our custody today...
34. Kendra & Hank Baskett
Aired: Mar 2, 2010 Kendra and Hank Baskett are here to tell us all about the spellbinding new se...
35. Single Staffers, Handler Edition
Aired: Mar 3, 2010 Please enjoy a very special Handler Edition of Single Staffers. Comedian Matt...
36. Gabourey Sidibe
Aired: Mar 4, 2010 From Precious, the Academy Award-nominated Gabourey Sidibe is here. TV person...
37. Kevin McKidd
Aired: Mar 8, 2010 Someone got some time away from the O.R., Grey's Anatomy's Kevin McKidd is he...
38. Chelsea Chelsea Bang Bang
Aired: Mar 9, 2010 Chelsea Chelsea Bang Bang is in stores now...You're welcome, everyone. Comedi...
39. Amy Ryan
Aired: Mar 10, 2010 Chelsea Chelsea Bang Bang is in stores now...You're welcome, everyone. Comedi...
40. Pretty Wild Cast
Aired: Mar 11, 2010 Alexis Neiers, Gabrielle Neiers and Tess Taylor are here from their aptly tit...
41. Shenae Grimes
Aired: Mar 15, 2010 90210's Shenae Grimes is here to give us the deets on all things West Beverly...
42. Rachael Harris
Aired: Mar 16, 2010 From the highly anticipated Diary of a Wimpy Kid, the purely entertaining Rac...
43. Avril Lavigne
Aired: Mar 17, 2010 We catch up with Avril Lavigne, who sings "Alice," the title song from Tim Bu...
44. Duane "Dog" Chapman
Aired: Mar 18, 2010 We're so thrilled to welcome the author of Where Mercy Is Shown, Mercy Is Giv...
45. Kelly Cutrone
Aired: Mar 22, 2010
46. Scott Wolf
Aired: Mar 23, 2010
47. Crispin Glover
Aired: Mar 24, 2010
48. Blake Shelton
Aired: Mar 25, 2010
49. Ludacris
Aired: Mar 29, 2010 Ludacris is back with his new album Battle of the Sexes and this time he's br...
50. Johnny Weir
Aired: Mar 30, 2010 Johnny Weir is here, and unfortunately our show is not "on ice" this week. Co...
51. Erykah Badu
Aired: Mar 31, 2010
52. Justin Bieber
Aired: Apr 1, 2010 Chuy Bravo wrote a book, Little Nuggets of Wisdom, and he's here to share the...
53. Jennifer Love Hewitt
Aired: Apr 5, 2010 Author of The Day I Shot Cupid, Jennifer Love Hewitt is here. Comedian Brad W...
54. Ed Asner
Aired: Apr 6, 2010 Find out how spunky Chelsea can really be when TV Icon and star of Up Ed Asne...
55. Blake MyCoskie
Aired: Apr 7, 2010 Things get real philanthropic up in here with Tom's Shoes founder Blake Mycos...
56. Taraji P. Henson
Aired: Apr 8, 2010 From the highly anticipated movie Date Night, the Academy Award-nominated Tar...
57. Tiny & Toya
Aired: Apr 12, 2010 From BET's Tiny & Toya, BFFs Tiny & Toya are here. Comedian Whitney Cummings,...
58. Our 500th Episode
Aired: Apr 13, 2010 Come celebrate a real milestone at Chelsea Lately—tonight's our 500th episode...
59. Dave Salmoni
Aired: Apr 14, 2010 Resident animal expert Dave Salmoni is back with some hopefully furry friends...
60. Erin Andrews & Maksim Chmerkovskiy
Aired: Apr 15, 2010 Dancing With the Stars' hottest couple Erin Andrews and Maksim Chmerkovskiy. ...
61. Gretchen Wilson
Aired: Apr 19, 2010
62. Amy & Matt Roloff
Aired: Apr 20, 2010
63. Katie Cassidy
Aired: Apr 21, 2010
64. Ted Allen
Aired: Apr 22, 2010
65. Michael Weatherly
Aired: Apr 26, 2010
66. Jerry Weintraub
Aired: Apr 27, 2010
67. Jeffrey Dean Morgan
Aired: Apr 28, 2010
68. Brooke Shields
Aired: Apr 29, 2010
69. Molly Ringwald
Aired: May 3, 2010
70. Busy Philipps
Aired: May 4, 2010
71. Monica
Aired: May 5, 2010
72. Michael Lewis
Aired: May 6, 2010
73. Amanda Seyfried
Aired: May 10, 2010
74. Laura Bell Bundy
Aired: May 11, 2010
75. Asian Singles with Jo Koy
Aired: May 13, 2010
76. Carson Kressley
Aired: May 17, 2010
77. Bradley Whitford
Aired: May 18, 2010
78. Marisa Miller
Aired: May 19, 2010
79. Mary Lynn Rajskub
Aired: May 20, 2010
80. Damon Wayans
Aired: May 24, 2010
81. James Van Praagh
Aired: May 25, 2010
82. Judge Lately
Aired: May 26, 2010
83. Tim Roth
Aired: May 31, 2010
84. Zach Gilford
Aired: Jun 1, 2010
85. Snoop Dogg and Mike Epps
Aired: Jun 2, 2010
86. Justin Halpern
Aired: Jun 3, 2010 The man behind all things Shit My Dad Says, Justin Halpern is here. Comedian ...
87. Colin Hanks
Aired: Jun 7, 2010 Tonight we welcome Colin Hanks, one of The Good Guys from the new Fox drama. ...
88. Clay Aiken
Aired: Jun 8, 2010 Clay Aiken is here, seriously, with his new CD Tried and True. Comedian Ben G...
89. Holly Madison
Aired: Jun 9, 2010 Holly Madison is back with her new show Holly's World. Comedian Chris Hardwic...
90. Stephen Moyer
Aired: Jun 10, 2010 True Blood is returning and Stephen Moyer is here, so get excited...or scared...
91. Denis Leary
Aired: Jun 14, 2010 Star of all things Rescue Me the hilarious Denis Leary is here. Comedian Stev...
92. Sarah McLachlan
Aired: Jun 15, 2010 We're getting a little Lilith tonight when Sarah McLachlan stops by and talks...
93. Lil Jon
Aired: Jun 16, 2010 We're getting crunk with Lil Jon and his new album Crunk Rock…YEAAAAHHHH! Com...
94. Roy Handler & Charley
Aired: Jun 17, 2010 Learn how to make cupcakes with Roy and Charley tonight. Comedian Brad Wollac...
95. A.J. Khubani
Aired: Jun 21, 2010 Learn about the borderline amazing new As Seen on TV Products with A.J. Khuba...
96. Mary McCormack
Aired: Jun 22, 2010 Star of In Plain Sight Mary McCormack graces us with her presence. Comedian J...
97. Ron Artest
Aired: Jun 23, 2010 Comedian Matt Braunger, comedian Moshe Kasher and comedian Guy Branum. Lakers...
98. Ashley Greene
Aired: Jun 24, 2010 Actress Ashley Greene on her new movie, "The Twilight Saga: Eclipse"; Round t...
99. T.I.
Aired: Jun 28, 2010 Rapper T.I. on his new album, "King Uncaged"; Round table discussion with com...
100. Bryce Dallas Howard
Aired: Jun 29, 2010 From the most-anticipated movie in the country, Eclipse, Bryce Dallas Howard ...
101. Joe's Crab Shack
Aired: Jun 30, 2010 Check out Chuy as the new spokesperson for Joe's Crab Shack...You're welcome ...
102. Sam Trammell
Aired: Jul 1, 2010 True Blood's favorite shapeshifter Sam Trammell is back. Comedian Bobby Lee, ...
103. Claire Smith
Aired: Jul 5, 2010 Learn about the summer's best drinks with Belvedere's Claire Smith. Comedian ...
104. Pharrell
Aired: Jul 6, 2010 Pharrell does a lot, like producing the soundtrack and composing the score fo...
105. Kristin Cavallari
Aired: Jul 8, 2010 Kristin Cavallari is here and has all the info you're dying to know about the...
106. Dave Salmoni
Aired: Jul 19, 2010 Canadian animal trainer Dave Salmoni on his new show, "Savaged with Dave Salm...
107. Susan Sarandon
Aired: Jul 20, 2010 Actress Susan Sarandon on her upcoming reality ping-pong series; Round table ...
108. Anna Paquin
Aired: Jul 21, 2010 Sink your teeth into this: tonight we welcome Anna Paquin from HBO's True Blo...
109. Arsenio Hall
Aired: Jul 22, 2010 Dust off your fists, girls, because Arsenio Hall is in the house. Comedian Ch...
110. Frank Grillo
Aired: Jul 26, 2010 Actor Frank Grillo on his show, "The Gates"; Round table discussion with comi...
111. Kathy Griffin
Aired: Jul 27, 2010 Comedian Kathy Griffin on her show, "Kathy Griffin: My Life on the D-List"; R...
112. Chicken Charlie
Aired: Jul 28, 2010 Fry cook Chicken Charlie discusses frying food; Round table discussion with c...
113. Ron Livingston
Aired: Jul 29, 2010 Actor Ron Livingston on his new film, "Dinner with Schmucks"; Round table dis...
114. Gabrielle Reece
Aired: Aug 2, 2010 Tonight's guest is volleyball pro Gabby Reece. At the Round Table: John Capar...
115. Lisa Lampanelli
Aired: Aug 3, 2010 Tonight's guest is actress Lisa Lampanelli. At the Round Table: Brad Wollack,...
116. Fat Joe
Aired: Aug 4, 2010 Fat Joe returns with his new album, The Darkside. Comedian Chris Franjola, ac...
117. Eva Mendes
Aired: Aug 5, 2010 From The Other Guys, Eva Mendes is here. Comedian Dan Levy, comedian Natasha ...
118. Bethenny Frankel
Aired: Aug 9, 2010 Star of Bravo's Bethenny Getting Married?, Bethenny Frankel is here. Comedian...
119. Margaret Cho
Aired: Aug 10, 2010 Margaret Cho tells us about her new comedy/music album Cho Dependent. Comedia...
120. Alanis Morissette
Aired: Aug 11, 2010 We're checking in with Alanis Morissette who's working her acting chops on th...
121. Extra Round Table
Aired: Aug 12, 2010 Extra Round Table. Comedian Jo Koy, comedian Sarah Colonna and comedian Jason...
122. Kim Raver
Aired: Aug 16, 2010 Grey's Anatomy star Kim Raver tells us about her foray into the Lifetime TV m...
123. Kim & Kourtney Kardashian
Aired: Aug 17, 2010 Kim and Kourtney Kardashian are here to make sure everyone is still Keeping U...
124. Jennifer Aniston
Aired: Aug 18, 2010 Jennifer Aniston is here telling us about her new film The Switch. Comedian J...
125. Elisabeth Shue
Aired: Aug 19, 2010 From the most frightening 3D movie of the summer, Piranha: 3D, Elisabeth Shue...
126. Eli Roth
Aired: Aug 23, 2010 Eli Roth tells us about his latest film The Last Exorcism. Comedian Chris Har...
127. Rufus Wainwright
Aired: Aug 24, 2010 Rufus Wainwright tells us about his tour and latest CD, All Days are Nights: ...
128. Jerry Springer
Aired: Aug 25, 2010 Jerry Springer tells us about his foray into game shows as host of GSN's Bagg...
129. Angie Harmon
Aired: Aug 26, 2010 Angie Harmon tells us about her hugely popular show Rizzoli & Isles. Comedian...
130. Jewel
Aired: Aug 30, 2010 Jewel returns and tells us about her new album, Sweet and Wild. Comedian Brad...
131. Louise Roe
Aired: Aug 31, 2010 Host of CW's Plain Jane Louise Roe is here to make over the staff of Chelsea ...
132. Extra Roundtable
Aired: Sep 1, 2010 You asked for more round table, tonight you're getting more round table. You'...
133. Mel B
Aired: Sep 2, 2010 Mel B. tells us about her new Style Network show Mel B: It's a Scary Life. Co...
134. Ne-Yo
Aired: Sep 6, 2010 R&B singer Ne-Yo on his new album, "Libra Scale "; Round table discussion wit...
135. B.o.B.
Aired: Sep 7, 2010 VMA performer and five-time nominee B.o.B is here with his No. 1 album B.o.B ...
136. Extra Roundtable
Aired: Sep 8, 2010 An extra-long Round Table. You're welcome, America. Comedian T. J. Miller, co...
137. Extra Roundtable
Aired: Sep 9, 2010 An extra-long Round Table. You're welcome, America. Comedian Ben Gleib, actre...
138. Emma Stone
Aired: Sep 13, 2010 From Easy A, the can-do-no-wrong-in-my-book Emma Stone is here. Comedian Chri...
139. Snooki and Pauly D
Aired: Sep 14, 2010 Get ready to GTL because Jersey Shore's Snooki and Pauly D are back. Comedian...
140. Usher
Aired: Sep 15, 2010 Usher has a new album, Versus, is on tour and is hanging out with us tonight,...
141. Jared Leto
Aired: Sep 16, 2010 Jared Leto, lead singer of the band '30 Seconds to Mars.' Comedian John Capar...
142. Meghan McCain
Aired: Sep 20, 2010 We welcome author of Dirty Sexy Politics, Meghan McCain. Comedian Josh Wolf, ...
143. Emily Rose
Aired: Sep 21, 2010 Emily Rose from SyFy's Haven is here. Comedian Matt Braunger, comedian Sarah ...
144. Laird Hamilton
Aired: Sep 22, 2010 We're pretty stoked that world-renowned surfer Laird Hamilton returns tonight...
145. Kristen Bell
Aired: Sep 23, 2010 From the hilarious movie You Again, Jersey Shore's No. 1 fan Kristen Bell is ...
146. Adam Levine
Aired: Sep 27, 2010 Adam Levine of Maroon 5 is here with their new album Hands All Over. Comedian...
147. Taye Diggs
Aired: Sep 28, 2010 Star of Private Practice Taye Diggs is here…he may or may not be wearing a sh...
148. Dax Shepard
Aired: Sep 29, 2010 Parenthood's Dax Shepard is here to discuss many a things, one being his new ...
149. AnnaLynne McCord
Aired: Sep 30, 2010 AnnaLynne McCord is here to give us the 411 on all things 90210. Comedian Chr...
150. Duane "Dog" Chapman, Beth Smith Chapman,
Aired: Oct 4, 2010 Dog the Bounty Hunter's Beth and Duane "Dog" Chapman grace our stage tonight....
151. Tommy Lee
Aired: Oct 5, 2010 Tommy Lee is here with his latest Methods of Mayhem project A Public Disservi...
152. Kelly Osbourne
Aired: Oct 6, 2010 Cohost of E!'s Fashion Police, Kelly Osbourne, is here. Comedian Jo Koy, come...
153. Trace Adkins
Aired: Oct 11, 2010 The cowboy himself, Trace Adkins, is back with his new album Cowboy's Back in...
154. Leah Remini
Aired: Oct 12, 2010 Cohost of the new CBS talk show The Talk, Leah Remini is here. Comedian Jo Ko...
155. Lauren Conrad
Aired: Oct 13, 2010 Author of Sugar and Spice and Lauren Conrad Style the very busy Lauren Conrad...
156. Amy Brenneman
Aired: Oct 14, 2010 From Private Practice, the delightful Amy Brenneman returns to the show tonig...
157. Johnny Knoxville
Aired: Oct 18, 2010 The biggest jackass of them all, Johnny Knoxville from Jackass 3D is here. Co...
158. Blake Shelton
Aired: Oct 19, 2010 The newest member of the Grand Ole Opry, Blake Shelton is here with his new a...
159. Lloyd Banks
Aired: Oct 20, 2010 Rapper Lloyd Banks. Comedian John Caparulo, comedian Whitney Cummings and com...
160. Jenny McCarthy
Aired: Oct 21, 2010 Jenny McCarthy is back with her latest book Love, Lust, and Faking It. Comedi...
161. Julian McMahon
Aired: Oct 25, 2010 From the film Red Julian McMahon graces us with his presence tonight. Comedia...
162. Milla Jovovich
Aired: Oct 26, 2010 Milla Jovovich returns to tell us about her new film Stone. Comedian Josh Wol...
163. Jennifer Nettles
Aired: Oct 27, 2010 Jennifer Nettles of Sugarland returns tonight with their new album The Incred...
164. Nick Swardson
Aired: Oct 28, 2010 From Nick Swardson's Pretend Time comedian Nick Swardson is here. Comedian Br...
165. Eddie Izzard
Aired: Nov 1, 2010 Eddie Izzard from Showtime's United States of Tara is here. Comedian Jo Koy, ...
166. Benji & Joel Madden
Aired: Nov 2, 2010 Benji and Joel Madden are here to tell us all about Good Charlotte's new albu...
167. Emily Procter
Aired: Nov 3, 2010 Probably the most pregnant cast member of CSI: Miami, Emily Procter is here. ...
168. Connie Britton
Aired: Nov 4, 2010 From dare I say the greatest television show of all time (Friday Night Lights...
169. Keenan Cahill
Aired: Nov 8, 2010 We've got YouTube sensation Keenan Cahill debuting his brand new video on the...
170. Kendra Wilkinson-Baskett
Aired: Nov 9, 2010 Kendra Wilkinson-Baskett is here to tell us all about the new season of her s...
171. Starsky & Cox
Aired: Nov 10, 2010 Find out how all of the stars align tonight with cosmic astrologists Starsky ...
172. Florence Welch
Aired: Nov 11, 2010 Florence Welch, from one of this year's hottest acts, Florence + the Machine,...
173. Monica Potter
Aired: Nov 15, 2010 From one of the best shows on TV, Parenthood, Monica Potter is here. Comedian...
174. Trey Songz
Aired: Nov 16, 2010 Trey Songz is bringing his Passion Pain and Pleasure (also the name of his ne...
175. Tom Bergeron
Aired: Nov 17, 2010 Dancing With the Stars' extraordinary host and Deb's BFF (sorry, Gary) Tom Be...
176. Nelly
Aired: Nov 18, 2010 Nelly is dropping by with his new album 5.0. This is for real, this is not ju...
177. Single security guards
Aired: Nov 22, 2010 It's the return of Single Staffers...just in time for the holiday season, you...
178. Dane Cook
Aired: Nov 23, 2010 Dane Cook is here with his greatest hits album, I Did My Best. Comedian Jo Ko...
179. Taylor Swift
Aired: Nov 24, 2010 Taylor Swift has a new album, called Speak Now, and she's here to tell us all...
180. Donald Schultz
Aired: Nov 26, 2010 Animal expert Donald Schultz is here with an alligator, a prairie dog and a r...
181. John Stamos
Aired: Nov 29, 2010 One of the greatest gifts television has ever given us, John Stamos who's bee...
182. Flo Rida
Aired: Nov 30, 2010 Flo Rida is here with his new album Only 1 Flo and hopefully some explanation...
183. Cee-Lo Green
Aired: Dec 1, 2010 Tonight we welcome The Lady Killer himself Cee-Lo Green. Topless Comedian Chr...
184. Kate Bosworth
Aired: Dec 2, 2010 From the new film The Warrior's Way Kate Bosworth is here. Comedian John Capa...
185. Tom Arnold
Aired: Dec 6, 2010
186. Lucy Liu
Aired: Dec 7, 2010
187. Keri Hilson
Aired: Dec 8, 2010
188. Kathy Griffi
Aired: Dec 9, 2010
189. Nicki Minaj
Aired: Dec 13, 2010
190. Cat Cora
Aired: Dec 14, 2010
191. Ciara
Aired: Dec 15, 2010
192. Amy Adams
Aired: Dec 16, 2010
193. Diddy-Dirty Money
Aired: Dec 20, 2010
194. Reese Witherspoon
Aired: Dec 21, 2010
195. Crystal Bowersox
Aired: Dec 22, 2010
196. Natasha Bedingfield
Aired: Dec 27, 2010
197. Keyshia Cole
Aired: Dec 29, 2010