Eliza Thornberry (Lacey Chabert) is not your ordinary kid. It's not just because she travels the world in an RV with her parents, famous nature-show hosts Nigel (Tim Curry) and Marianne (Jodi Carlisle). Eliza is doubly unique because she was granted the magical ability to talk with and understand animals. With her teenage sister Debbie (Danielle Harris), her wild-boy foster brother Donnie (Flea), and her pet monkey Darwin (Tom Kane), Eliza gets involved with many different wildlife (and wild adventures).
When the Thornberrys are forced to spend the night in the middle of the savan...