20 years after meddling into the bank heist of a notorious robber named Gasback, Vash the Stampede is heading towards Macca City. Rumors say that the legendary thief might appear there causing an enormous influx of bounty hunters in the area who want to collect the $300,000,000 prize for his head.
A gunfighter with a strict no-kill policy, Vash the Stampede arrives in a town full of bounty hunters competing to collect the reward for catching a robber he saved 20 years ago.