Mr. Freeze is living in the arctic with his cryogenically-frozen wife. When a submarine destroys her containment capsule, he has to find someone to "donate" a new heart for her. His search turns up one donor with the right blood type: Barbara (Batgirl) Gordon. Her kidnapping sends Batman and Robin on a hurried chase to free her in time.
Batman & Mr. Freeze: SubZero
When Mr. Freeze, desperate to save his dying wife, kidnaps Barbara Gordon (Batgirl) as an involuntary organ donor, Batman and Robin must find her before the operation can begin.